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Journal of Clinical Microbiology, January 2003, p. 509-511, Vol. 41, No. 1
0095-1137/03/$08.00+0 DOI: 10.1128/JCM.41.1.509-511.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.
| CASE REPORT |
B. Hanau-Berçot,1 L. Raskine,1 J. Riahi,1 J. L. Gaillard,2 and M. J. Sanson-Le-Pors1*
Service of Bacteriology-Virology, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, Paris,1 Service of Bacteriology-Virology, Raymond Poincarré Hospital, Assistance Publique-Hôpitaux de Paris, Garches, France2
Received 3 July 2002/ Returned for modification 2 September 2002/ Accepted 6 October 2002
Clostridium difficile, the most common cause of antibiotic-associated diarrhea, is occasionally isolated from extraintestinal sites and is usually found as part of a polymicrobial flora. We report a case of brain empyema that occurred after the recurrent intestinal carriage of a nontoxigenic strain of C. difficile. Brain abscess cultures contained both toxigenic and nontoxigenic isolates. Pulsed-field gel electrophoresis showed that nontoxigenic isolates from the intestine and from the brain were identical.
Present address: Service de Bactériologie-Virologie, Hôpital Louis Mourier, 92701 Colombes Cedex, France.
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