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Journal of Clinical Microbiology, October 2003, p. 4842-4843, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4842-4843.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Volume Effect on Sensitivity of Nucleic Acid Amplification Tests for Detection of Chlamydia trachomatis in Urine Specimens from Females

Jeanne Moncada,1* Joan M. Chow,1,2 and Julius Schachter1

Department of Laboratory Medicine,1 Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California2

Received 20 February 2003/ Returned for modification 9 May 2003/ Accepted 16 June 2003

Nucleic acid amplification tests (NAATs) for the detection of Chlamydia trachomatis are routinely used on first-catch urine (FCU) specimens. We analyzed data from a head-to-head comparison of NAATs on female FCU specimens and found that the volume of urine collected could affect test performance.

* Corresponding author. Mailing address: Chlamydia Laboratory at SFGH, Department of Laboratory Medicine, Bldg. 30, Room 416, University of California, San Francisco, CA 94110. Phone: (415) 824-5115. Fax: (415) 821-8945. E-mail: jevemo{at}itsa.ucsf.edu.

Journal of Clinical Microbiology, October 2003, p. 4842-4843, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4842-4843.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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