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Journal of Clinical Microbiology, October 2003, p. 4892-4893, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4892-4893.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Serial Granulocyte Transfusions as a Treatment for Sepsis Due to Multidrug-Resistant Pseudomonas aeruginosa in a Neutropenic Patient

Ying-Wei Lin,* Souichi Adachi, Ken-Ichiro Watanabe, Katsutsugu Umeda, and Tatsutoshi Nakahata

Department of Pediatrics, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan

Received 7 July 2003/ Accepted 11 July 2003

The emergence of multidrug-resistant Pseudomonas aeruginosa (MRPA) has become a major clinical problem. We successfully treated MRPA sepsis in a neutropenic patient undergoing peripheral blood stem cell transplantation with serial granulocyte transfusions. Granulocyte transfusion should be considered as a treatment for severe infection in patients with neutropenia.

* Corresponding author. Present address: ATC/GB/CCR/NCI/NIH, 301 N. Stonestreet Ave., Rockville, MD 20892-4605. Phone: (301) 402-8843. Fax: (301) 402-3134. E-mail: linying{at}mail.nih.gov.

Journal of Clinical Microbiology, October 2003, p. 4892-4893, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4892-4893.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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