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Journal of Clinical Microbiology, October 2003, p. 4898-4900, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4898-4900.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Successful Outcome of Disseminated Fusarium Infection with Skin Localization Treated with Voriconazole and Amphotericin B-Lipid Complex in a Patient with Acute Leukemia

Isabelle Durand-Joly,1,2* Serge Alfandari,3 Zinnédine Benchikh,1 Marion Rodrigue,1 Ana Espinel-Ingroff,4 Benoit Catteau,5 Christophe Cordevant,2 Daniel Camus,1,2 Eduardo Dei-Cas,1,2 Francis Bauters,6 Laurence Delhaes,1,2 and Stéphane De Botton6

Parasitologie-Mycologie, Faculté de Médecine,1 Service de Dermatologie,5 Service des Maladies du Sang, CHRU de Lille,6 EA-3609-IFR17, Institut Pasteur de Lille, Lille,2 Maladies Infectieuses, Tourcoing, France,3 Medical Mycology Research Laboratory, Medical College of Virginia, Richmond, Virginia4

Received 17 March 2003/ Returned for modification 16 June 2003/ Accepted 3 July 2003

A disseminated Fusarium oxysporum infection with skin localization was diagnosed in a woman with a relapse of B-acute leukemia during induction chemotherapy. The infection was refractory to amphotericin B-lipid complex alone but responded successfully when voriconazole was added.

* Corresponding author. Mailing address: Parasitologie-Mycologie, Faculté de Médecine et CHRU de Lille, 1 Place Verdun, 59045 Lille, France. Phone: 33 3 20 44 55 77. Fax: 33 3 20 44 42 64. E-mail: i-joly{at}chru-lille.fr..

Journal of Clinical Microbiology, October 2003, p. 4898-4900, Vol. 41, No. 10
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.10.4898-4900.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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