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Journal of Clinical Microbiology, November 2003, p. 5288-5290, Vol. 41, No. 11
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.11.5288-5290.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Infections in International Pregnancy Study: Performance of the Optical Immunoassay Test for Detection of Group B Streptococcus

Jadsada Thinkhamrop,^1* Sompop Limpongsanurak,² Mario R. Festin,³ Sean Daly,⁴ Anne Schuchat,⁵ Pisake Lumbiganon,¹ Elizabeth Zell,⁶ Tsungai Chipato,⁷ Aye Aye Win,⁸ Mindy J. Perilla,⁵ Jorge E. Tolosa,⁹ and Cynthia G. Whitney⁵

Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen,¹ Department of Obstetrics and Gynecology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand,² Department of Clinical Epidemiology, University of the Philippines, Manila, The Philippines,³ Coombe Women's Hospital, Dublin, Ireland,⁴ Respiratory Diseases Branch,⁵ Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, National Centers for Infectious Diseases, Centers for Disease ControlPrevention, Atlanta, Georgia,⁶ Department of Obstetrics and Gynaecology, University of Zimbabwe School of Medicine, Harare, Zimbabwe,⁷ Department of Obstetrics and Gynaecology, Institute of Medicine, Yangon, Myanmar,⁸ Department of Obstetrics and Gynecology, Divisions of Research in Reproductive Health and Maternal-Fetal Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania⁹

Received 28 February 2003/ Returned for modification 16 April 2003/ Accepted 27 August 2003

We evaluated the Strep B optical immunoassay (OIA; ThermoBiostar, Inc.) for detecting light and heavy group B streptococcus colonization in 1,306 pregnant women. The women were examined at 20 to 32 weeks gestation and were from six countries. Compared to culture, the sensitivity and specificity of OIA were 13.3 and 98.4%, respectively, for light colonization and 41.5 and 97.7%, respectively, for heavy colonization.

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* Corresponding author. Mailing address: Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Phone: 66-43-246445. Fax: 66-43-348395. E-mail: Jadsada{at}kku.ac.th.

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Journal of Clinical Microbiology, November 2003, p. 5288-5290, Vol. 41, No. 11
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.11.5288-5290.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

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