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Journal of Clinical Microbiology, February 2003, p. 857-859, Vol. 41, No. 2
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.2.857-859.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Catheter-Related Sepsis Due to Rhodotorula glutinis

Po-Ren Hsueh,1,2* Lee-Jene Teng,1,3 Shen-Wu Ho,1,3 and Kwen-Tay Luh1,2

Departments of Laboratory Medicine,1 Internal Medicine, National Taiwan University Hospital,2 School of Medical Technology, National Taiwan University College of Medicine, Taipei, Taiwan3

Received 8 July 2002/ Returned for modification 3 October 2002/ Accepted 21 October 2002

We describe a central venous catheter-related (Port-A-Cath; Smiths Industries Medical Systems [SIMS] Deltec, Inc., St. Paul, Minn.) infection caused by Rhodotorula glutinis in a 51-year-old man with nasopharyngeal carcinoma. He was treated with fluconazole for 8 weeks and had the catheter removed. Two isolates of R. glutinis recovered from blood specimens (one obtained via peripheral veins and one via the catheter) before administration of fluconazole and one recovered from the removed catheter 17 days after initiation of fluconazole therapy exhibited high-level resistance to fluconazole (MICs, >256 µg/ml). These three isolates were found to belong to a single clone on the basis of identical antibiotypes determined by the E test (PDM Epsilometer; AB Biodisk, Solna, Sweden) and biotypes determined by API ID32 C (bioMerieux, Marcy I'Etoile, France) and their identical random amplified polymorphic DNA patterns.

* Corresponding author. Mailing address: Department of Laboratory Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Rd., Taipei, Taiwan. Phone: 886-2-23123456, ext. 5363. Fax: 886-2-23224263. E-mail: hsporen{at}ha.mc.ntu.edu.tw.

Journal of Clinical Microbiology, February 2003, p. 857-859, Vol. 41, No. 2
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.2.857-859.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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