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Journal of Clinical Microbiology, May 2003, p. 2166-2169, Vol. 41, No. 5
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.5.2166-2169.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

A Serotype V Clone Is Predominant among Erythromycin-Resistant Streptococcus agalactiae Isolates in a Southwestern Region of Germany

Ulrich von Both,1 Michael Ruess,1 Urban Mueller,1 Kirsten Fluegge,1 Anna Sander,2 and Reinhard Berner1*

University Children's Hospital, D-79106 Freiburg,1 Institute for Medical Microbiology and Hygiene, University of Freiburg, D-79104 Freiburg, Germany2

Received 11 October 2002/ Returned for modification 14 November 2002/ Accepted 14 February 2003

One hundred ninety-three Streptococcus agalactiae isolates of neonatal origin and 146 isolates from adult women were analyzed for macrolide resistance and investigated for clonality. Among erythromycin-resistant isolates, serotype V turned out to be the most frequent. Comparative pulsed-field gel electrophoresis analysis revealed genetic clustering of resistant strains and predominance of a single clone family within an otherwise heterogeneous serotype V population.


* Corresponding author. Mailing address: University Children's Hospital, Mathildenstrasse 1, D-79106 Freiburg, Germany. Phone: 49-761-270-4300. Fax: 49-761-270-4481. E-mail: berner{at}kikli.ukl.uni-freiburg.de.


Journal of Clinical Microbiology, May 2003, p. 2166-2169, Vol. 41, No. 5
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.5.2166-2169.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.




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