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Journal of Clinical Microbiology, May 2003, p. 2206-2208, Vol. 41, No. 5
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.5.2206-2208.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Search for Cytolethal Distending Toxin Production among Fecal Escherichia Coli Isolates from Brazilian Children with Diarrhea and without Diarrhea

Lilian R. M. Marques,1* Ana T. Tavechio,1 Cecília M. Abe,2,{dagger} and Tânia A. T. Gomes2

Seção de Bacteriologia, Instituto Adolfo Lutz, CEP 01246-902,1 Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo-Escola Paulista de Medicina, CEP 04023-062, São Paulo SP, Brazil2

Received 16 September 2002/ Returned for modification 16 November 2002/ Accepted 31 January 2003

The enteropathogenic role of cytolethal distending toxin-producing Escherichia coli was investigated by searching sequences homologous to the cdt genes of an O86 strain among 2,074 isolates from 200 children with acute diarrhea and 200 controls in Brazil. Only one (0.5%) diarrheic child and two (1.0%) nondiarrheic controls harbored cdt-positive isolates.

* Corresponding author. Mailing address: Seção de Bacteriologia, Instituto Adolfo Lutz, Av. Dr. Arnaldo, 355-9° Andar, Cerqueira César, São Paulo, CEP 01246-902 SP, Brazil. Phone: 55-11-3068-2892. Fax: 55-11-3088-3041. E-mail: lmarques{at}ial.sp.gov.br.

{dagger} Present address: Institute of Child Health, University of Birmingham, B4 6LH Birmingham, United Kingdom.

Journal of Clinical Microbiology, May 2003, p. 2206-2208, Vol. 41, No. 5
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.5.2206-2208.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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