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Journal of Clinical Microbiology, June 2003, p. 2279-2281, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2279-2281.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Nationwide Surveillance for Staphylococcus aureus with Reduced Susceptibility to Vancomycin in Korea

Departments of Internal Medicine,¹ Laboratory Medicine, Seoul National University College of Medicine,³ Clinical Research Institute, Seoul National University Hospital, Seoul 110-744, Republic of Korea²

Received 21 January 2003/ Returned for modification 18 February 2003/ Accepted 6 March 2003

Methicillin-resistant Staphylococcus aureus (MRSA) accounts for more than 70% of S. aureus isolates from tertiary hospitals in Korea. Clinical isolates of S. aureus were collected from eight provincial, university-affiliated hospitals during the period from June 1999 to January 2001 for nationwide surveillance. All isolates were screened for reduced susceptibility to vancomycin by using brain heart infusion agar containing 4 µg of vancomycin per milliliter. Population analysis and the determination of the MIC of vancomycin were done for the isolates which grew on the screening agar plates. Of 682 total isolates, MRSA accounted for 64% (439 of 682). Of 27 (4%) isolates that grew on the screening agar plates, none showed the heteroresistance phenotype. No strains with reduced susceptibility to vancomycin were identified.

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