This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kranker, S.
Right arrow Articles by Dahl, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kranker, S.
Right arrow Articles by Dahl, J.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, June 2003, p. 2282-2288, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2282-2288.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Longitudinal Study of Salmonella enterica Serotype Typhimurium Infection in Three Danish Farrow-to-Finish Swine Herds

Søren Kranker,* Lis Alban, Jaap Boes, and Jan Dahl

National Committee for Pig Production, Danish Bacon and Meat Council, Department of Veterinary Research and Development, DK-1609 Copenhagen V, Denmark

Received 13 September 2002/ Returned for modification 16 December 2002/ Accepted 5 March 2003

A longitudinal study of the infection dynamics of Salmonella enterica was carried out with three Danish farrow-to-finish swine herds. To account for variations in Salmonella shedding over time, litters from each herd were divided into two cohorts. Each cohort consisted of 30 pigs, for a total of 180 pigs. Pigs were individually monitored by monthly bacteriologic and serologic examinations from weaning to slaughter. At weaning, individual sows were examined bacteriologically and serologically. At slaughter, cecal contents, ileocecal lymph nodes, and carcass swab samples were obtained from 131 pigs. A total of 88 pigs were found to be shedding Salmonella on one or more occasions. Only the Salmonella serotype Typhimurium was detected during the study period. At weaning, no sows or piglets were found to be shedding, but a serological reaction was detected in 11 sows. The prevalence in culture peaked in the nursery and subsequently declined to undetectable levels before slaughter. The seroprevalence peaked approximately 60 days after the peak prevalence in culture. Salmonella was detected in individual fecal samples at least once in 53% of the pigs, and 62% of the pigs were seropositive more than once. Only 3.7% of all pigs were found to be culture positive on more than one occasion. Piglets from seroreacting sows had a significantly (P = 0.0339) lower probability of shedding in the nursery. Under the assumption that shedding lasted at least 1 or 2 weeks, the average shedding time was estimated to have been 18 or 26 days. An association between serology, on-farm bacteriology, and Salmonella prevalence in culture at slaughter was shown. Marked differences in prevalence in sera and prevalence in culture between cohorts and within herds were observed. These differences emphasize the need for caution when using point estimates in on-farm interventions and surveillance in subclinically infected swine herds.

* Corresponding author. Mailing address: National Committee for Pig Production, Danish Bacon and Meat Council, Department of Veterinary Research and Development, Axeltorv 3, DK-1609, Copenhagen V, Denmark. Phone: 45-33 73 25 27. Fax: 45-33 14 57 56. E-mail: skr{at}danishmeat.dk.

Journal of Clinical Microbiology, June 2003, p. 2282-2288, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2282-2288.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Dorr, P. M., Tadesse, D. A., Zewde, B. M., Fry, P., Thakur, S., Gebreyes, W. A. (2009). Longitudinal Study of Salmonella Dispersion and the Role of Environmental Contamination in Commercial Swine Production Systems. Appl. Environ. Microbiol. 75: 1478-1486 [Abstract] [Full Text]  
  • Holley, R., Walkty, J., Blank, G., Tenuta, M., Ominski, K., Krause, D., Ng, L.-K. (2008). Examination of Salmonella and Escherichia coli Translocation from Hog Manure to Forage, Soil, and Cattle Grazed on the Hog Manure-treated Pasture. J. Environ. Qual. 37: 2083-2092 [Abstract] [Full Text]  
  • Jensen, A. N., Dalsgaard, A., Stockmarr, A., Nielsen, E. M., Baggesen, D. L. (2006). Survival and Transmission of Salmonella enterica Serovar Typhimurium in an Outdoor Organic Pig Farming Environment.. Appl. Environ. Microbiol. 72: 1833-1842 [Abstract] [Full Text]  
  • Malorny, B., Hoorfar, J. (2005). Toward Standardization of Diagnostic PCR Testing of Fecal Samples: Lessons from the Detection of Salmonellae in Pigs. J. Clin. Microbiol. 43: 3033-3037 [Full Text]  
  • Loynachan, A. T., Harris, D. L. (2005). Dose Determination for Acute Salmonella Infection in Pigs. Appl. Environ. Microbiol. 71: 2753-2755 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»