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Journal of Clinical Microbiology, June 2003, p. 2680-2682, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2680-2682.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Increased Prevalence of G1P[4] Genotype among Children with Rotavirus-Associated Gastroenteritis in Metropolitan Detroit

Nahed M. Abdel-Haq,1,2,3* Robert A. Thomas,1,2,3 Basim I. Asmar,1,2 Viera Zacharova,3 and William D. Lyman1,3

Department of Pediatrics, Wayne State University School of Medicine,1 Division of Infectious Diseases, Children's Hospital of Michigan,2 Children's Research Center of Michigan, Wayne State University, Detroit, Michigan 482013

Received 20 February 2002/ Returned for modification 20 July 2002/ Accepted 13 March 2003

The G and P genotypes of rotavirus stool isolates from 100 children were determined by reverse transcription-PCR and nucleotide sequencing. G1P[4] was the most prevalent genotype(41%), followed by G1P[8] (16%) and G4P[4] (14%). The G genoypes detected were G1 (73%), G4 (17.4%), G9 (6.3%), and G2 (2.8%). The P genotypes were P[4] (71%) and P[8] (29%). Coinfection with more than one G genotype occurred in 12 patients, and coinfection with more than one P genotype occurred in 11 patients.

* Corresponding author. Mailing address: Division of Infectious Diseases, Children's Hospital of Michigan, 3901 Beaubien Blvd., Detroit, MI 48201. Phone: (313) 745-5863. Fax: (313) 993-8846. E-mail: nabdel{at}dmc.org.

Journal of Clinical Microbiology, June 2003, p. 2680-2682, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2680-2682.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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