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Journal of Clinical Microbiology, June 2003, p. 2748-2751, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2748-2751.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Sequence Analysis of the Matrix (M2) Protein Gene of Avian Pneumovirus Recovered from Turkey Flocks in the United States

Arshud M. Dar,1,2 Shirin Munir,1,2 Sagar M. Goyal,3 and Vivek Kapur1,2*

Biomedical Genomics Center,1 Department of Veterinary PathoBiology,2 Veterinary Diagnostic Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 551083

Received 17 June 2002/ Returned for modification 18 December 2002/ Accepted 9 March 2003

We here report the comparative sequence and phylogenetic analysis of the avian pneumovirus subgroup C (APV C) matrix (M2) gene of cell culture-adapted isolates and clinical samples. Limited heterogeneity was observed among the M2 sequences, suggesting that diagnostic tests and vaccines against APV C are likely to exhibit broad cross-reactivity.

* Corresponding author. Mailing address: Department of Microbiology and Biomedical Genomics Center, University of Minnesota, 1971 Commonwealth Ave., St. Paul, MN 55108. Phone: (612) 625-7712. Fax: (612) 625-5203. E-mail: vkapur{at}umn.edu.

Journal of Clinical Microbiology, June 2003, p. 2748-2751, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2748-2751.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2003 by the American Society for Microbiology. All rights reserved.