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Journal of Clinical Microbiology, June 2003, p. 2760-2762, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2760-2762.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Emergence of Novel Human Group A Rotavirus G12 Strains in India

Soma Das,1 V. Varghese,1 S. Chaudhury,1 P. Barman,1 S. Mahapatra,2 K. Kojima,3 S. K. Bhattacharya,4,5 T. Krishnan,1 R. K. Ratho,6 G. P. Chhotray,2 A. C. Phukan,7 N. Kobayashi,3 and T. N. Naik1,5*

Division of Virology,1 Division of Clinical Medicine, National Institute of Cholera and Enteric Diseases,4 ICMR Virus Unit, GB-4 ID and BG Hospital Campus, Calcutta 700010,5 Division of Microbiology, Regional Medical Research Centre, Bhubaneshwar 751023,2 Department of Virology, Post-Graduate Institute of Medical Education and Research, Chandigarh 160012,6 Division of Microbiology, Regional Medical Research Centre for North-East, Dibrugarh 768001, India,7 Department of Hygiene, Sapporo Medical University School of Medicine, Sapporo 060, Japan3

Received 9 July 2002/ Returned for modification 29 November 2002/ Accepted 6 March 2003

Three rare human G12 strains were detected from diarrheic clinical samples of children (<8 months of age) in Calcutta during a routine surveillance study of rotaviral diarrhea in India. The VP7 genes of G12 strains and their products showed maximum homology (97 to 99% at the nucleotide level and 98% at the amino acid level, respectively) with those of two recently reported G12 strains (from the United States and Thailand) but lesser homology with those of prototype G12 strain L26.

* Corresponding author. Mailing address: Division of Virology, National Institute of Cholera and Enteric Diseases, P-33 CIT Rd., Scheme XM, Beliaghata, Calcutta 700010, India. Phone: 91-33-2350 0448. Fax: 91-33-2350 5066. E-mail: tnaik{at}satyam.net.in.

Journal of Clinical Microbiology, June 2003, p. 2760-2762, Vol. 41, No. 6
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.6.2760-2762.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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