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Journal of Clinical Microbiology, July 2003, p. 3334-3335, Vol. 41, No. 7
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.7.3334-3335.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Evaluation of [13C]Urea Breath Test and Helicobacter pylori Stool Antigen Test for Diagnosis of H. pylori Infection in Children from a Developing Country

Luciana de Carvalho Costa Cardinali,1 Gifone Aguiar Rocha,1 Andreia Maria Camargos Rocha,1 Sílvia Beleza de Moura,2 Taciana de Figueiredo Soares,1 Ana Maria Braz Esteves,1 Ana Margarida Miguel Ferreira Nogueira,3 Mônica Maria Demas Álvares Cabral,3 Anfrisina Sales Teles de Carvalho,1 Paulo Bitencourt,4 Alexandre Ferreira,5 and Dulciene Maria Magalhães Queiroz1*

Laboratory of Research in Bacteriology,1 Department of Pathology, Faculdade de Medicina,3 Instituto de Ciências Biológicas, UFMG,2 Hospital Felício Rocho,4 Hospital das Clínicas UFMG, Belo Horizonte, Brazil5

Received 19 February 2003/ Returned for modification 1 April 2003/ Accepted 11 April 2003

The [13C]urea breath test (13C-UBT) and Helicobacter pylori stool antigen test (HpSA) for the diagnosis of H. pylori infection in children were validated. The sensitivity, specificity, and positive and negative predictive values were 93.8, 99.1, 97.8, and 98.0%, respectively, for the 13C-UBT and 96.9, 100, 100, and 98.0%, respectively, for HpSA. Both tests are appropriate for diagnosing H. pylori infection in children.

* Corresponding author. Mailing address: Laboratory of Research in Bacteriology, Faculdade de Medicina, UFMG, Av. Alfredo Balena, 190/4026-30130-100 Belo Horizonte, Brazil. Phone and fax: 5531-32742767. E-mail: dqueiroz{at}medicina.ufmg.br.

Journal of Clinical Microbiology, July 2003, p. 3334-3335, Vol. 41, No. 7
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.7.3334-3335.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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