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Journal of Clinical Microbiology, July 2003, p. 3368-3371, Vol. 41, No. 7
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.7.3368-3371.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Tsukamurella Conjunctivitis: a Novel Clinical Syndrome

Patrick C. Y. Woo,1 Antonio H. Y. Ngan,1 Susanna K. P. Lau,1 and Kwok-Yung Yuen1,2*

Department of Microbiology, The University of Hong Kong,1 HKU-Pasteur Research Centre, Hong Kong2

Received 17 March 2003/ Returned for modification 13 April 2003/ Accepted 19 April 2003

In this report, we describe the first three cases of Tsukamurella conjunctivitis in the literature. All three patients presented with congestion of one eye with small amounts of serous discharge for 1 to 2 days. All three recovered after 10 days of treatment with polymyxin B-neomycin or chloramphenicol eyedrops. Sequencing of the 16S rRNA genes of the three isolates recovered from the serous discharge of the three patients showed that they were all Tsukamurella species. The phenotypic characteristics of the isolate obtained from one patient best fit the phenotypic profile of Tsukamurella pulmonis, whereas those of the other two best fit that of Tsukamurella tyrosinosolvens.


* Corresponding author. Mailing address: Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong. Phone: (852) 28554892. Fax: (852) 28551241. E-mail: hkumicro{at}hkucc.hku.hk.


Journal of Clinical Microbiology, July 2003, p. 3368-3371, Vol. 41, No. 7
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.7.3368-3371.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.




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