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Journal of Clinical Microbiology, July 2003, p. 3392-3394, Vol. 41, No. 7
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.7.3392-3394.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Analysis of Genetic Identity of North American Anaplasma phagocytophilum Strains by Pulsed-Field Gel Electrophoresis

J. S. Dumler,^1* K. M. Asanovich,^1, and J. S. Bakken²

Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205,¹ Infectious Diseases, SMDC Health System, Duluth, Minnesota 55805²

Received 3 March 2003/ Returned for modification 25 March 2003/ Accepted 27 March 2003

Biological and geographic heterogeneity of anthropozoonosis caused by Anaplasma phagocytophilum is poorly understood. Seven North American A. phagocytophilum strains were compared by PFGE. The average genome size was 1.58 Mbp, and restriction patterns were identical. New World strains of A. phagocytophilum have a large genome and a high degree of genetic uniformity.

Present address: College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.

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