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Journal of Clinical Microbiology, August 2003, p. 3970-3972, Vol. 41, No. 8
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.8.3970-3972.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Genetic Relationship between Streptococcus pneumoniae Isolates from Nasopharyngeal and Cerebrospinal Fluid of Two Infants with Pneumococcal Meningitis

Ana Lucia Sampaio Sgambatti de Andrade,1* Fabiana Cristina Pimenta,1 Maria Cristina C. Brandileone,2 Cristina Aparecida Laval,3 Maria Luiza Guerra,2 João Guimarães de Andrade,1 and Jose Luis Di Fabio4

Institute of Tropical Pathology and Public Health, Federal University of Goias,1 Secretariat of Health, Municipality of GoiÂnia, GoiÂnia,3 Adolfo Lutz Institute, São Paulo, Brazil,2 Pan American Health Organization, Division of Vaccines and Immunization, Washington, D.C.4

Received 24 February 2003/ Returned for modification 1 April 2003/ Accepted 17 May 2003

The molecular epidemiology of Streptococcus pneumoniae isolates from carriage and cerebrospinal fluid (CSF) concurrently recovered from the same individual has not yet been reported. By using pulsed-field gel electrophoresis, we demonstrated the genetic linkage among strains from CSF and nasopharynges of two children with pneumococcal meningitis.

* Corresponding author. Mailing address: Instituto de Patologia Tropical e Saúde Pública—UFG, Rua Delenda R Melo, S/N, Setor Universitário, GoiÂnia, CEP 74 605-050, Brazil. Phone and fax: 55-62-2027942. E-mail: ana{at}iptsp.ufg.br.

Journal of Clinical Microbiology, August 2003, p. 3970-3972, Vol. 41, No. 8
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.8.3970-3972.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2003 by the American Society for Microbiology. All rights reserved.