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Journal of Clinical Microbiology, September 2003, p. 4411-4414, Vol. 41, No. 9
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.9.4411-4414.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Outbreak of Serogroup C Meningococcal Disease Caused by a Variant of Neisseria meningitidis Serotype 2a ET-15 in a Community of Men Who Have Sex with Men

Raymond S.W. Tsang,1* Lori Kiefer,2,{dagger} Dennis K. S. Law,1 Jan Stoltz,1 Rita Shahin,2 Shirley Brown,3 and Frances Jamieson3

National Microbiology Laboratory, Population and Public Health Branch, Health CanadaWinnipeg, Manitoba,1 Toronto Public Health,2 Ontario Public Health Laboratory, Ministry of Health and Long Term Care, Toronto, Ontario, Canada3

Received 7 February 2003/ Returned for modification 9 April 2003/ Accepted 3 June 2003

We describe an outbreak, in a community of men who have sex with men, of serogroup C meningococcal disease caused by a genetic variant of the serotype 2a ET-15 Neisseria meningitidis characterized by a point mutation in the gene coding for the serotype 2a antigen. A microbiological characterization of the outbreak strain is presented in this report.

* Corresponding author. Mailing address: Central Nervous System Infection and Vaccine Preventable Bacterial Diseases Division, National Microbiology Laboratory, 1015 Arlington St., Winnipeg, Manitoba, R3E 3R2, Canada. Phone: (204) 789-6020. Fax: (204) 789-2018. E-mail: rtsang{at}hc-sc.gc.ca.

{dagger} Present address: Department of Public Health Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Journal of Clinical Microbiology, September 2003, p. 4411-4414, Vol. 41, No. 9
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.9.4411-4414.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2003 by the American Society for Microbiology. All rights reserved.