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Journal of Clinical Microbiology, September 2003, p. 4428-4430, Vol. 41, No. 9
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.9.4428-4430.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Prevalence of Fragilysin Gene in Bacteroides fragilis Isolates from Blood and Other Extraintestinal Samples

Ina Foulon, Denis Piérard,* Gaëtan Muyldermans, Kristof Vandoorslaer, Oriane Soetens, Paul Rosseel, and Sabine Lauwers

Department of Microbiology, Academisch Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium

Received 18 March 2003/ Returned for modification 22 April 2003/ Accepted 3 June 2003

Of 166 Bacteroides fragilis isolates, 26.2% of 103 isolates from blood and 20.6% of 63 extraintestinal isolates harbored the fragilysin gene (difference not statistically significant). Clinical characteristics and evolution were comparable in patients with B. fragilis bacteremia with or without this enterotoxin. Fragilysin seems not to be an important virulence factor in B. fragilis disease.

* Corresponding author. Mailing address: Department of Microbiology, Academisch Ziekenhuis Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090 Brussels, Belgium. Phone: 32 2 477 50 02. Fax: 32 2 477 50 15. E-mail: denis.pierard{at}az.vub.ac.be.

Journal of Clinical Microbiology, September 2003, p. 4428-4430, Vol. 41, No. 9
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.9.4428-4430.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Sears, C. L. (2009). Enterotoxigenic Bacteroides fragilis: a Rogue among Symbiotes. Clin. Microbiol. Rev. 22: 349-369 [Abstract] [Full Text]  
  • Robertson, K. P., Smith, C. J., Gough, A. M., Rocha, E. R. (2006). Characterization of Bacteroides fragilis Hemolysins and Regulation and Synergistic Interactions of HlyA and HlyB. Infect. Immun. 74: 2304-2316 [Abstract] [Full Text]  


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