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Journal of Clinical Microbiology, September 2003, p. 4435-4437, Vol. 41, No. 9
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.9.4435-4437.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Streptococcus pneumoniae Endocarditis: Persistence of DNA on Heart Valve Material 7 Years after Infectious Episode

S. Branger,1 J. P. Casalta,1 G. Habib,2 F. Collard,3 and D. Raoult1*

Laboratoire de Microbiologie,1 Service de Cardiologie,2 Service de Chirurgie Cardiaque, Centre Hospitalier Universitaire La Timone, Marseille, France3

Received 6 March 2003/ Returned for modification 11 June 2003/ Accepted 3 July 2003

We amplified by PCR and sequenced Streptococcus pneumoniae rpoB from DNA of the cardiac valve of a man who had presented with pneumococcal endocarditis 7 years earlier. Histopathologically, the valve did not show evidence of endocarditis. This case raises the question of persistence of DNA without any evidence of infection.

* Corresponding author. Mailing address: Unité des Rickettsies, Faculté de Médecine, 27 blvd. Jean Moulin, 13385 Marseille Cédex 5, France. Phone: 33 04 91 38 55 17. Fax: 33 04 91 83 03 90. E-mail: Didier.Raoult{at}medecine.univ-mrs.fr.

Journal of Clinical Microbiology, September 2003, p. 4435-4437, Vol. 41, No. 9
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.9.4435-4437.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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