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Journal of Clinical Microbiology, November 2004, p. 5332-5333, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5332-5333.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Convenience of Serum for Visceral Leishmaniasis Diagnosis by PCR

Equipe de Recherche sur les Leishmanioses, Faculté de Médecine, Université de Nice—Sophia-Antipolis and Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Nice, Nice, France,¹ Centre de Transfusion Sanguine, Monaco²

Received 24 February 2004/ Returned for modification 27 February 2004/ Accepted 25 July 2004

In this retrospective study, the usefulness of a PCR performed on serum for primary diagnosis and monitoring of Mediterranean visceral leishmaniasis (MVL) was assessed. In the case of primary diagnosis of MVL, the serum PCR showed a sensitivity of 97% and a specificity of 95%, with positive and negative predictive values of 94 and 97%, respectively.

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