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Journal of Clinical Microbiology, November 2004, p. 5334-5336, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5334-5336.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Utility of Molecular Identification in Opportunistic Mycotic Infections: a Case of Cutaneous Alternaria infectoria Infection in a Cardiac Transplant Recipient

G. Lo Cascio,1* M. Ligozzi,2 L. Maccacaro,2 and R. Fontana2

Servizio di Microbiologia, Azienda Ospedaliera di Verona, Ospedale Policlinico G. B. Rossi,1 Sezione di Microbiologia, Dipartimento di Patologia, Università degli Studi di Verona, Verona, Italy2

Received 2 January 2004/ Returned for modification 14 May 2004/ Accepted 5 July 2004

We report on a case of cutaneous infection caused by Alternaria infectoria in a cardiac transplant recipient. A rapid molecular diagnosis was obtained by sequence analysis of the internal transcribed spacer domain of the 5.8S ribosomal DNA region amplified from colonies developed on Sabouraud medium. Treatment consisted of a combination of systemic antifungal therapy, first with amphotericin B and then with itraconazole.


* Corresponding author. Mailing address: Servizio di Microbiologia, Azienda Ospedaliera di Verona, Ospedale Policlinico G. B. Rossi, Piazzale Scuro, 10, 37134 Verona, Italy. Phone: 0039-045-8074682. Fax: 0039-045-584159. E-mail: giuliana.locascio{at}azosp.vr.it.


Journal of Clinical Microbiology, November 2004, p. 5334-5336, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5334-5336.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.