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Journal of Clinical Microbiology, November 2004, p. 5375-5377, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5375-5377.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Characterization of a West Nile Virus Isolate from a Human on the Gulf Coast of Texas

Bruno P. Granwehr,1,2 Li Li,2 Charles T. Davis,2 David W. C. Beasley,2 and Alan D. T. Barrett2*

Division of Infectious Diseases, Department of Internal Medicine,1 Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas2

Received 8 October 2003/ Returned for modification 14 December 2003/ Accepted 24 April 2004

Genetic characterization of a human cerebrospinal fluid West Nile virus isolate from Beaumont, Texas, revealed several nucleotide changes and amino acid substitutions that differentiated it from all other North American strains isolated to date, suggesting that isolates from the Texas Gulf Coast may form a unique genetic group among North American strains.

* Corresponding author. Mailing address: Department of Pathology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-0609. Phone: (409) 772-6662. Fax: (409) 772-2500. E-mail: abarrett{at}utmb.edu.

Journal of Clinical Microbiology, November 2004, p. 5375-5377, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5375-5377.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.





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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2004 by the American Society for Microbiology. All rights reserved.