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Journal of Clinical Microbiology, November 2004, p. 5378-5380, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5378-5380.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Clonal Spread of IMP-1-Producing Pseudomonas aeruginosa in Two Hospitals in Singapore

Tse Hsien Koh,* Grace Chee Yeng Wang, and Li-Hwei Sng

Department of Pathology, Singapore General Hospital, Singapore, Singapore

Received 8 March 2004/ Returned for modification 16 April 2004/ Accepted 20 June 2004

Thirty-six isolates of carbapenem-resistant Pseudomonas aeruginosa were studied. Pulsed-field gel electrophoresis revealed the presence of two clones. One clone carried a blaIMP-1 gene identical to that first described in Japan. The other clone carried a blaIMP-1 variant containing four silent mutations. One isolate with a unique pulsed-field gel electrophoresis pattern contained blaIMP-7.

* Corresponding author. Mailing address: Department of Pathology, Singapore General Hospital, 1 Hospital Dr., 169608 Singapore, Singapore. Phone: 65-6321-4505. Fax: 65-6222-6826. E-mail: gptthk{at}sgh.com.sg.

Journal of Clinical Microbiology, November 2004, p. 5378-5380, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5378-5380.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Strateva, T., Yordanov, D. (2009). Pseudomonas aeruginosa - a phenomenon of bacterial resistance. J Med Microbiol 58: 1133-1148 [Abstract] [Full Text]  


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