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Journal of Clinical Microbiology, December 2004, p. 5877-5880, Vol. 42, No. 12
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.12.5877-5880.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Broth Microdilution Susceptibility Testing of Francisella tularensis: Quality Control Limits for Nine Antimicrobial Agents and Three Standard Quality Control Strains

Steven D. Brown,* Karen Krisher, and Maria M. Traczewski

Clinical Microbiology Institute, Wilsonville, Oregon

Received 30 June 2004/ Accepted 24 August 2004

For broth microdilution susceptibility tests of Francisella tularensis, Mueller-Hinton broth with 2% Isovitalex is recommended. Using that medium, we studied three standard control strains tested with nine antimicrobial agents potentially efficacious for treating tularemia. An eight-laboratory collaborative study generated the data needed to propose appropriate MIC control limits.


* Corresponding author. Mailing address: Clinical Microbiology Institute, 9725 S.W. Commerce Circle—Suite A1, Wilsonville, OR 97070. Phone: (503) 682-3232. Fax: (503) 682-2065. E-mail: SBrown{at}clinmicroinst.com.


Journal of Clinical Microbiology, December 2004, p. 5877-5880, Vol. 42, No. 12
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.12.5877-5880.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.