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Journal of Clinical Microbiology, December 2004, p. 5928-5930, Vol. 42, No. 12
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.12.5928-5930.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Detection of Resistance to Gatifloxacin and Moxifloxacin in Streptococcus pneumoniae with the VITEK 2 Instrument

J. H. Jorgensen,1* S. A. Crawford,1 L. M. McElmeel,1 and C. G. Whitney2

Department of Pathology, University of Texas Health Science Center, San Antonio, Texas,1 Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia2

Received 6 July 2004/ Returned for modification 30 July 2004/ Accepted 18 August 2004

A group of 72 pneumococcal isolates resistant or intermediate to levofloxacin and 124 pneumococcal isolates susceptible to fluoroquinolones were tested by the VITEK 2 instrument using investigational test cards and by a broth microdilution reference method. The VITEK 2 instrument performed well, detecting 52 of 60 (86.7%) gatifloxacin-resistant isolates and 22 of 23 moxifloxacin-resistant isolates, and did not falsely classify any susceptible isolates as resistant.

* Corresponding author. Mailing address: Department of Pathology, University of Texas Health Science Center, 7703 Floyd Curl Dr., San Antonio, TX 78229-3900. Phone: (210) 567-4088. Fax: (210) 567-2367. E-mail: jorgensen{at}uthscsa.edu.

Journal of Clinical Microbiology, December 2004, p. 5928-5930, Vol. 42, No. 12
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.12.5928-5930.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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