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Journal of Clinical Microbiology, February 2004, p. 811-815, Vol. 42, No. 2
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.2.811-815.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Comparison of LCx with Other Current Viral Load Assays for Detecting and Quantifying Human Immunodeficiency Virus Type 1 RNA in Patients Infected with the Circulating Recombinant Form A/G (CRF02)

Alessandra Amendola, Licia Bordi, Claudio Angeletti, Enrico Girardi, Giuseppe Ippolito, and Maria R. Capobianchi*

National Institute for Infectious Diseases "Lazzaro Spallanzani," Rome, Italy

Received 11 June 2003/ Returned for modification 25 September 2003/ Accepted 11 November 2003

LCx was compared to other assays in measuring human immunodeficiency virus type 1 (HIV-1) CRF02 viremia. LCx showed significant but low correlation with the other methods. Values of <2.60 log10 cp/ml were observed in 29.6% of specimens with LCx and in only 14.8% with bDNA and PCR, suggesting suboptimal performance of LCx with CRF02.

* Corresponding author. Mailing address: Laboratorio di Virologia, Istituto Nazionale per le Malattie Infettive I.R.C.C.S. "Lazzaro Spallanzani," Via Portuense 292, 00149 Rome, Italy. Phone: 39-655170434. Fax: 39-65582346. E-mail: capobianchi{at}inmi.it.

Journal of Clinical Microbiology, February 2004, p. 811-815, Vol. 42, No. 2
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.2.811-815.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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