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Journal of Clinical Microbiology, March 2004, p. 1333-1336, Vol. 42, No. 3
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.3.1333-1336.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

A Canine Parvovirus Mutant Is Spreading in Italy

Department of Animal Health and Wellbeing, University of Bari, Bari,¹ Department of Pathology and Infectious Diseases, University of Messina, Messina, Italy²

Received 13 December 2002/ Returned for modification 26 May 2003/ Accepted 11 November 2003

By antigenic and genetic characterization of canine parvovirus type 2 (CPV-2) strains collected in 2001 and 2002 in Italy, it was possible to observe the spread of viruses with an unusual mutation, Glu-426, affecting a major antigenic epitope of CPV-2. Out of 67 strains analyzed, 49 (73.13%) were characterized as CPV-2a, 6 (8.95%) were characterized as CPV-2b, and 12 (17.91%) were characterized as the Glu-426 mutant.

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