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Journal of Clinical Microbiology, April 2004, p. 1713-1715, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1713-1715.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Dual Toxin-Producing Strain of Clostridium botulinum Type Bf Isolated from a California Patient with Infant Botulism

Jason R. Barash and Stephen S. Arnon*

Infant Botulism Treatment and Prevention Program, California Department of Health Services, Richmond, California 94804

Received 9 September 2003/ Returned for modification 14 November 2003/ Accepted 23 December 2003

A retrospective study of Clostridium botulinum strains isolated from patients from California with infant botulism identified the fourth known C. botulinum strain that produces both type B and type F botulinum toxins. This unique strain represented 0.12% of the California infant botulism case isolates from 1976 to 2003. The relative concentrations of type B and F toxins produced were temperature dependent.

* Corresponding author. Mailing address: Infant Botulism Treatment and Prevention Program, California Department of Health Services, 850 Marina Bay Pkwy., Room E361, Richmond, CA 94804. Phone: (510) 231-7600. Fax: (510) 231-7609. E-mail: sarnon{at}dhs.ca.gov.

Journal of Clinical Microbiology, April 2004, p. 1713-1715, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1713-1715.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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