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Journal of Clinical Microbiology, April 2004, p. 1779-1781, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1779-1781.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Usefulness of Toxoplasma gondii-Specific Recombinant Antigens in Serodiagnosis of Human Toxoplasmosis

H. Pietkiewicz,¹ E. Hiszczyska-Sawicka,² J. Kur,² E. Petersen,^3,4 H. V. Nielsen,³ M. Stankiewicz,⁵ I. Andrzejewska,⁶ and P. Myjak^1*

Department of Tropical Parasitology, Interfaculty Institute of Maritime and Tropical Medicine, Medical University of Gdask, 81-519 Gdynia,¹ Department of Microbiology, Gdask University of Technology, 80-952 Gdask,² Department of Biology and Medical Parasitology, Medical University of Pozna, 87-100 Pozna, Poland,⁴ Laboratory of Parasitology, Statens Seruminstitut, DK-2300 Copenhagen, Denmark,³ Animal and Food Sciences Division, Lincoln University, Canterbury, New Zealand,⁵ Department of Laboratory Medicine, Karolinska Institute, S14186 Stockholm, Sweden⁶

Received 16 July 2003/ Returned for modification 10 November 2003/ Accepted 9 January 2004

Toxoplasma gondii SAG1, GRA1, and GRA7 recombinant antigens may be regarded as tools for the detection of T. gondii immunoglobulin G antibodies in persons with chronic and acute toxoplasmosis. GRA7 is more correlated with acute toxoplasmosis. A combination of these antigens will increase the sensitivity of enzyme-linked immunosorbent assays.

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