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Journal of Clinical Microbiology, April 2004, p. 1803-1806, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1803-1806.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Establishment of an Active Laboratory-Based Surveillance for Bacterial Meningitis in Croatia and Molecular Characterization of Neisseria meningitidis Isolates Causing Meningococcal Disease That Were Collected in the Year 2000, the First Year of Activity

A. Boras,1* T. Jeren,1 C. T. Sacchi,2 S. Schmink,2 D. Bozinovic,1 B. Barsic,1 N. E. Rosenstein,2 T. Popovic,2 and the Croatian Study Group for Bacterial Meningitis{dagger}

University Hospital for Infectious Diseases, Zagreb, Croatia,1 Meningitis and Special Pathogens Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia2

Received 13 August 2003/ Returned for modification 19 September 2003/ Accepted 29 September 2003

In 2000, 23 Neisseria meningitidis (meningococcal [Men]) isolates were collected in Croatia through an active laboratory-based surveillance for bacterial meningitis (17 Men serogroup B [MenB], 4 MenC, 1 MenW135, and 1 nongroupable isolate). Molecular characterization revealed a substantial level of diversity with only six isolates belonging to electrophoretic type 5 (ET-5) and ET-37 hypervirulent complexes.

* Corresponding author. Mailing address: Epidemiologic Investigations Laboratory, Meningitis and Special Pathogens Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 17/2209, GS 34, 1600 Clifton Rd., Atlanta, GA 30333. Phone: (404) 639-1730. Fax: (404) 639-3172. E-mail: txp1{at}cdc.gov.

{dagger} Contributing members of the Croatian Study Group for Bacterial Meningitis are listed in Acknowledgments.

Journal of Clinical Microbiology, April 2004, p. 1803-1806, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1803-1806.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.





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