JCM Figure table search 04
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lefevre, J.
Right arrow Articles by Coutlée, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lefevre, J.
Right arrow Articles by Coutlée, F.
Journal of Clinical Microbiology, May 2004, p. 2212-2215, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2212-2215.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Human Papillomavirus Type 16 Viral Load Is Higher in Human Immunodeficiency Virus-Seropositive Women with High-Grade Squamous Intraepithelial Lesions Than in Those with Normal Cytology Smears

Jonas Lefevre,1,2 Catherine Hankins,3,4 Deborah Money,5 Anita Rachlis,6 Karina Pourreaux,4 The Canadian Women's HIV Study Group,{dagger} and François Coutlée1,2*

Laboratoire de Virologie Moléculaire, Centre de Recherche du Centre Hospitalier de l'Université de Montréal,1 Département de Microbiologie et Immunologie, Université de Montréal,2 Joint Departments of Epidemiology, Biostatistics and Occupational Health, McGill University,3 Direction de la Santé Publique de Montréal-Centre, Institut National de la Santé Publique du Québec, Montréal, Québec,4 Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia,5 Department of Epidemiology and Biostatistics, University of Toronto, Toronto, Ontario, Canada6

Received 10 November 2003/ Returned for modification 12 January 2004/ Accepted 26 January 2004

Human papillomavirus type 16 (HPV-16) viral load in cervicovaginal lavage samples collected from 66 human immunodeficiency virus-seropositive women was inversely correlated with blood CD4 count (P = 0.002). HPV-16 viral load was 81-fold higher in women with cervical smears suggestive of high-grade lesions (median, 4,425,883 copies/µg of DNA) than in women with normal smears (median, 54,576), controlling for age (P = 0.006).


* Corresponding author. Mailing address: Département de Microbiologie et Infectiologie, Hôpital Notre-Dame du Centre Hospitalier de l'Université de Montréal, 1560 Sherbrooke est, Montréal (Québec), H2L 4M1, Canada. Phone: (514) 890-8000, ext. 25162. Fax: (514) 412-7512. E-mail: francois.coutlee{at}ssss.gouv.qc.ca.

{dagger} Contributing members of The Canadian Women's HIV Study Group are listed in Acknowledgments.


Journal of Clinical Microbiology, May 2004, p. 2212-2215, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2212-2215.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2004 by the American Society for Microbiology. All rights reserved.