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Journal of Clinical Microbiology, May 2004, p. 2216-2217, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2216-2217.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Comparison of Chlorhexidine and Tincture of Iodine for Skin Antisepsis in Preparation for Blood Sample Collection

Joan Barenfanger,1* Cheryl Drake,1 Jerry Lawhorn,1 and Steven J. Verhulst2

Laboratory Medicine, Memorial Medical Center,1 Division of Statistics and Research Consulting, School of Medicine, Southern Illinois University, Springfield, Illinois2

Received 29 September 2003/ Returned for modification 10 January 2004/ Accepted 9 February 2004

Rates of contamination of blood cultures obtained when skin was prepared with iodine tincture versus chlorhexidine were compared. For iodine tincture, the contamination rate was 2.7%; for chlorhexidine, it was 3.1%. The 0.41% difference is not statistically significant. Chlorhexidine has comparable effectiveness and is safer, cheaper, and preferred by staff, so it is an alternative to iodine tincture.

* Corresponding author. Mailing address: Laboratory Medicine, Memorial Medical Center, 701 N. First St., Springfield, IL 62781. Phone: (217) 788-3000. Fax: (217) 788-5577. E-mail: barenfanger.joan{at}mhsil.com.

Journal of Clinical Microbiology, May 2004, p. 2216-2217, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2216-2217.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Hall, K. K., Lyman, J. A. (2006). Updated Review of Blood Culture Contamination. Clin. Microbiol. Rev. 19: 788-802 [Abstract] [Full Text]  


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