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Journal of Clinical Microbiology, May 2004, p. 2326-2328, Vol. 42, No. 5
0095-1137/04/$08.00+0 DOI: 10.1128/JCM.42.5.2326-2328.2004
Glycerophosphodiester Phosphodiesterase Gene (glpQ) of Borrelia lonestari Identified as a Target for Differentiating Borrelia Species Associated with Hard Ticks (Acari:Ixodidae)
Rendi Murphree Bacon,1* Mark A. Pilgard,1 Barbara J. B. Johnson,1 Sandra J. Raffel,2 and Tom G. Schwan2
Bacterial Zoonoses Branch, Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80521,1
Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 598402
Received 23 September 2003/
Returned for modification 7 January 2004/
Accepted 27 January 2004
A glpQ ortholog was identified in DNA from Borrelia lonestari-positive Amblyomma americanum, providing further evidence that B. lonestari is more closely related to the relapsing fever group spirochetes than to borreliae that cause Lyme disease. This finding provides a basis for developing diagnostic assays to differentiate species of borrelia transmitted by hard ticks.
* Corresponding author. Mailing address: Bacterial Zoonoses Branch, CDC/NCID/DVBID, P.O. Box 2087, Fort Collins, CO 80522. Phone: (970) 266-3528. Fax: (970) 221-6476. E-mail:
rbacon{at}cdc.gov.
Journal of Clinical Microbiology, May 2004, p. 2326-2328, Vol. 42, No. 5
0095-1137/04/$08.00+0 DOI: 10.1128/JCM.42.5.2326-2328.2004
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