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Journal of Clinical Microbiology, May 2004, p. 2341-2344, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2341-2344.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Clinical Case of Endocarditis due to Trichosporon inkin and Antifungal Susceptibility Profile of the Organism

Jose M. Ramos,1 Manuel Cuenca-Estrella,2* Felix Gutierrez,1 Matilde Elia,3 and Juan L. Rodriguez-Tudela2

Unidad de Enfermedades Infecciosas, Servicio de Medicina,1 Servicio de Microbiología, Hospital General Universitario de Elche, Alicante,3 Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain2

Received 9 December 2003/ Returned for modification 14 January 2004/ Accepted 10 February 2004

A fatal case of Trichosporon inkin prosthetic endocarditis is reported. The isolation sites and susceptibility profiles of 10 other isolates are also reviewed. Four strains were recovered from cutaneous or subcutaneous samples, four were recovered from urine, one was recovered from peritoneal liquid, and one was recovered from bone. Voriconazole and amphotericin B had the most potent activities in vitro against the isolates, with MIC geometric means of 0.11 and 0.30 µg/ml, respectively.


* Corresponding author. Mailing address: Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2, 28220 Majadahonda (Madrid), Spain. Phone: 34-91-5097961. Fax: 34-91-5097966. E-mail: mcuenca-estrella{at}isciii.es.


Journal of Clinical Microbiology, May 2004, p. 2341-2344, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2341-2344.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.




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