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Journal of Clinical Microbiology, June 2004, p. 2802-2805, Vol. 42, No. 6
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.6.2802-2805.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Molecular Characterization and Phylogenetic Study of Newcastle Disease Virus Isolates from Recent Outbreaks in Eastern Uganda

Maxwell O. Otim,1,2* Henrik Christensen,2 Poul H. Jørgensen,3 Kurt J. Handberg,3 and Magne Bisgaard2

Livestock Health Research Institute, Tororo, Uganda,1 Department of Veterinary Pathobiology, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C,2 Danish Veterinary Institute, DK-8200 Århus N, Denmark3

Received 3 December 2003/ Returned for modification 27 January 2004/ Accepted 9 March 2004

Newcastle disease virus isolates from chickens in eastern Uganda in 2001 were found to be velogenic by fusion protein cleavage site sequence analysis and biological characterization; the intracerebral pathogenicity index was 1.8. Analysis of their hemagglutinin-neuraminidase protein gene sequences revealed a novel genotype unrelated to those that caused previous outbreaks.

* Corresponding author. Mailing address: Livestock Health Research Institute, P.O. Box 96, Tororo, Uganda. Phone: 256 77997450. Fax: 256 41 321070. E-mail: Maxwell_ot{at}yahoo.com.

Journal of Clinical Microbiology, June 2004, p. 2802-2805, Vol. 42, No. 6
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.6.2802-2805.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Qin, Z.-M., Tan, L.-T., Xu, H.-Y., Ma, B.-C., Wang, Y.-L., Yuan, X.-Y., Liu, W.-J. (2008). Pathotypical Characterization and Molecular Epidemiology of Newcastle Disease Virus Isolates from Different Hosts in China from 1996 to 2005. J. Clin. Microbiol. 46: 601-611 [Abstract] [Full Text]  


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