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Journal of Clinical Microbiology, June 2004, p. 2825-2828, Vol. 42, No. 6
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.6.2825-2828.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Outbreak of Infection with Hepatitis A Virus (HAV) Associated with a Foodhandler and Confirmed by Sequence Analysis Reveals a New HAV Genotype IB Variant

Maria Chironna,1* Pierluigi Lopalco,1 Rosa Prato,2 Cinzia Germinario,1 Salvatore Barbuti,1,2 and Michele Quarto1

Hygiene Section, Department of Internal Medicine and Public Health, University of Bari,1 Osservatorio Epidemiologico Regione Puglia, Coordinating Center for Notifiable Infectious Diseases, Bari, Italy2

Received 30 July 2003/ Returned for modification 27 October 2003/ Accepted 9 March 2004

An outbreak of infection with hepatitis A virus associated with a foodhandler and involving 26 subjects occurred in Southern Italy. Sequence analysis of the VP3-VP1 and VP1-P2A junctions confirmed that the outbreak was due to a point source and allowed the identification of a new genotype IB variant. This report confirms the usefulness of sequence-based molecular fingerprinting during outbreaks.

* Corresponding author. Mailing address: Hygiene Section, Department of Internal Medicine and Public Health, University of Bari, Policlinico Piazza G, Cesare 11, 70124 Bari, Italy. Phone: (39) 080 5592328. Fax: (39) 080 5478472. E-mail: m.chironna{at}igiene.uniba.it.

Journal of Clinical Microbiology, June 2004, p. 2825-2828, Vol. 42, No. 6
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.6.2825-2828.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Nainan, O. V., Xia, G., Vaughan, G., Margolis, H. S. (2006). Diagnosis of Hepatitis A Virus Infection: a Molecular Approach. Clin. Microbiol. Rev. 19: 63-79 [Abstract] [Full Text]  


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