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Journal of Clinical Microbiology, July 2004, p. 3346-3349, Vol. 42, No. 7
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.7.3346-3349.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Evaluation of Indirect Fluorescence Antibody Assay for Detection of Bartonella clarridgeiae and Seroprevalence of B. clarridgeiae among Patients with Suspected Cat Scratch Disease

Hidehiro Tsuneoka,1* Akiko Umeda,2 Masato Tsukahara,2 and Kohsuke Sasaki1

Department of Pathology,1 Faculty of Health Sciences, Yamaguchi University School of Medicine, Ube, Japan2

Received 5 January 2004/ Returned for modification 5 March 2004/ Accepted 10 April 2004

The possibility of Bartonella clarridgeiae being a causative agent of cat scratch disease (CSD) was investigated by using indirect fluorescence antibody assays with 288 suspected CSD patients. Immunoglobulin G antibody to noncocultivated B. clarridgeiae was suitable only for detection of B. clarridgeiae antibody. Significant cross-reactivity between Bartonella henselae and B. clarridgeiae was noted, and no CSD case caused by B. clarridgeiae was detected.

* Corresponding author. Mailing address: Department of Clinical Laboratory, Yamaguchi Kouseiren Nagato Hospital, Nagato City, Yamaguchi-ken 759-4101, Japan. Phone: 81-837-22-2409. Fax: 81-837-22-6542. E-mail: htsuneoka{at}mx52.tiki.ne.jp.

Journal of Clinical Microbiology, July 2004, p. 3346-3349, Vol. 42, No. 7
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.7.3346-3349.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.





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