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Journal of Clinical Microbiology, July 2004, p. 3350-3352, Vol. 42, No. 7
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.7.3350-3352.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Use of Two Sensitive and Specific Immunoblot Markers, Em70 and Em90, for Diagnosis of Alveolar Echinococcosis

Department of Parasitology, School of Medicine, Ege University,¹ Department of Parasitology, School of Medicine, Dokuz Eylul University, Izmir,² Department of Surgery, School of Medicine, Atatürk University, Erzurum, Turkey³

Received 20 December 2003/ Returned for modification 19 February 2004/ Accepted 21 March 2004

Antibodies against Echinococcus multilocularis metacestodes were screened by immunoblotting sera from patients with alveolar echinococcosis (n = 39), cystic echinococcosis (n = 109), or other parasitic infections (n = 66) and healthy individuals (n = 32). Two antigens, approximately 70 and 90 kDa, are found to be valuable for confirmatory diagnosis, with a sensitivity and specificity of 100 and 99.51%, respectively.