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Journal of Clinical Microbiology, August 2004, p. 3877-3880, Vol. 42, No. 8
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.8.3877-3880.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Surveillance of Methicillin-Resistant Staphylococcus aureus in a Pediatric Hospital in Mexico City during a 7-Year Period (1997 to 2003): Clonal Evolution and Impact of Infection Control

M. E. Velazquez-Meza,1,2 M. Aires de Sousa,2 G. Echaniz-Aviles,1 F. Solórzano-Santos,3 G. Miranda-Novales,3 J. Silva-Sanchez,1 and H. de Lencastre2,4*

Instituto Nacional de Salud Pública, Centro de Investigaciónes Sobre Enfermedades Infecciosas, Cuernavaca, Morelos,1 Hospital de Pediatría, Centro Medico Nacional, Siglo XXI-IMSS, Mexico City, México,3 Laboratorio de Genética Molecular, Instituto de Tecnología Química e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal,2 Laboratory of Microbiology, The Rockefeller University, New York, New York 100214

Received 12 January 2004/ Returned for modification 24 February 2004/ Accepted 28 April 2004

Between 1997 and 2000 a single multidrug-susceptible methicillin-resistant Staphylococcus aureus clone, M (sequence type 30 [ST30]-staphylococcal cassette chromosome mec [SCCmec] type IV), was present in a pediatric hospital in Mexico City, Mexico. In 2001 the international multidrug-resistant New York-Japan clone (ST5-SCCmec type II) was introduced into the hospital, completely replacing clone M by 2002.

* Corresponding author. Mailing address: The Rockefeller University, 1230 York Ave., New York, NY 10021. Phone: (212) 327-8278. Fax: (212) 327-8688. E-mail: lencash{at}rockefeller.edu.

Journal of Clinical Microbiology, August 2004, p. 3877-3880, Vol. 42, No. 8
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.8.3877-3880.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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