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Journal of Clinical Microbiology, August 2004, p. 3901-3903, Vol. 42, No. 8
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.8.3901-3903.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Intrafamilial Spread of the Same Clarithromycin-Resistant Helicobacter pylori Infection Confirmed by Molecular Analysis

Ikue Taneike,1 Keibun Suzuki,2 Saori Nakagawa,1 and Tatsuo Yamamoto1*

Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi-dori, Niigata,1 Department of Pediatrics, Shigaraki National Hospital, Shiga, Japan2

Received 8 January 2004/ Returned for modification 8 March 2004/ Accepted 3 April 2004

Clarithromycin-resistant Helicobacter pylori (CRHP) is increasing worldwide, especially in children. We report a family case in which both the mother and child were infected with CRHP. DNA analysis revealed that all of the mother's and daughter's isolates were indistinguishable, suggesting that the same CRHP strain spread between the family members. The spread of CRHP within families may be increasing.

* Corresponding author. Mailing address: Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 757 Ichibanchou, Asahimachidori, Niigata, Japan. Phone: 81-25-227-2050. Fax: 81-25-227-0762. E-mail: tatsuoy{at}med.niigata-u.ac.jp.

Journal of Clinical Microbiology, August 2004, p. 3901-3903, Vol. 42, No. 8
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.8.3901-3903.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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Copyright © 2004 by the American Society for Microbiology. All rights reserved.