This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ko, K. S.
Right arrow Articles by Song, J.-H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ko, K. S.
Right arrow Articles by Song, J.-H.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, January 2005, p. 421-426, Vol. 43, No. 1
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.1.421-426.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Distribution of Major Genotypes among Methicillin-Resistant Staphylococcus aureus Clones in Asian Countries

Kwan Soo Ko,1 Ji-Young Lee,1 Ji Yoeun Suh,1 Won Sup Oh,2 Kyong Ran Peck,2 Nam Yong Lee,3 and Jae-Hoon Song1,2*

Asian-Pacific Research Foundation for Infectious Diseases,1 Division of Infectious Diseases,2 Department of Laboratory Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea3

Received 1 July 2004/ Returned for modification 8 September 2004/ Accepted 13 September 2004

To investigate the evolutionary pattern and genotypic characteristics of methicillin-resistant Staphylococcus aureus (MRSA) strains in the Asian region, 74 MRSA strains isolated from 12 Asian countries were analyzed by multilocus sequence typing (MLST) and SCCmec typing. Overall, a total of 16 genotypes based on sequence type and SCCmec types were identified among MRSA strains from Asian countries. Data revealed two major genotypes of MRSA strains in Asia, with unique geographic distributions. By MLST analysis, all strains from Korea and Japan except one belonged to clonal complex 5 (CC5) while most MRSA isolates from other Asian countries belonged to CC239. SCCmec typing showed that most isolates from Korea and Japan were SSmec type II whereas SCCmec type III (or IIIA) was the most common type in strains from other Asian countries. Our data documented a unique geographic distribution and evolutionary pattern of MRSA clones in Asia.

* Corresponding author. Mailing address: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine Asian-Pacific Research Foundation for Infectious Diseases, 50 II-won dong, Kangnam-ku, Seoul 135-710, Korea. Phone: 82-2-3410-0320. Fax: 82-2-3410-0328. E-mail: jhsong{at}ansorp.org.

Journal of Clinical Microbiology, January 2005, p. 421-426, Vol. 43, No. 1
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.1.421-426.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Walther, B., Monecke, S., Ruscher, C., Friedrich, A. W., Ehricht, R., Slickers, P., Soba, A., Wleklinski, C.-G., Wieler, L. H., Lubke-Becker, A. (2009). Comparative Molecular Analysis Substantiates Zoonotic Potential of Equine Methicillin-Resistant Staphylococcus aureus. J. Clin. Microbiol. 47: 704-710 [Abstract] [Full Text]  
  • Liu, Y., Wang, H., Du, N., Shen, E., Chen, H., Niu, J., Ye, H., Chen, M. (2009). Molecular Evidence for Spread of Two Major Methicillin-Resistant Staphylococcus aureus Clones with a Unique Geographic Distribution in Chinese Hospitals. Antimicrob. Agents Chemother. 53: 512-518 [Abstract] [Full Text]  
  • Aires-de-Sousa, M., Correia, B., de Lencastre, H., and the Multilaboratory Project Collaborators, (2008). Changing Patterns in Frequency of Recovery of Five Methicillin-Resistant Staphylococcus aureus Clones in Portuguese Hospitals: Surveillance over a 16-Year Period. J. Clin. Microbiol. 46: 2912-2917 [Abstract] [Full Text]  
  • Severin, J. A., Lestari, E. S., Kuntaman, K., Melles, D. C., Pastink, M., Peeters, J. K., Snijders, S. V., Hadi, U., Duerink, D. O., van Belkum, A., Verbrugh, H. A., on behalf of the Antimicrobial Resistance in Indon, (2008). Unusually High Prevalence of Panton-Valentine Leukocidin Genes among Methicillin-Sensitive Staphylococcus aureus Strains Carried in the Indonesian Population. J. Clin. Microbiol. 46: 1989-1995 [Abstract] [Full Text]  
  • Feil, E. J., Nickerson, E. K., Chantratita, N., Wuthiekanun, V., Srisomang, P., Cousins, R., Pan, W., Zhang, G., Xu, B., Day, N. P. J., Peacock, S. J. (2008). Rapid Detection of the Pandemic Methicillin-Resistant Staphylococcus aureus Clone ST 239, a Dominant Strain in Asian Hospitals. J. Clin. Microbiol. 46: 1520-1522 [Abstract] [Full Text]  
  • Park, C., Lee, D.-G., Kim, S. W., Choi, S.-M., Park, S. H., Chun, H.-S., Choi, J.-H., Yoo, J.-H., Shin, W. S., Kang, J. H., Kim, J. H., Lee, S. Y., Kim, S. M., Pyun, B. Y. (2007). Predominance of Community-Associated Methicillin-Resistant Staphylococcus aureus Strains Carrying Staphylococcal Chromosome Cassette mec Type IVA in South Korea. J. Clin. Microbiol. 45: 4021-4026 [Abstract] [Full Text]  
  • Kim, E. S., Song, J. S., Lee, H. J., Choe, P. G., Park, K. H., Cho, J. H., Park, W. B., Kim, S.-H., Bang, J.-H., Kim, D.-M., Park, K. U., Shin, S., Lee, M. S., Choi, H. J., Kim, N. J., Kim, E.-C., Oh, M.-d., Kim, H. B., Choe, K. W. (2007). A survey of community-associated methicillin-resistant Staphylococcus aureus in Korea. J Antimicrob Chemother 60: 1108-1114 [Abstract] [Full Text]  
  • Amorim, M. L., Faria, N. A., Oliveira, D. C., Vasconcelos, C., Cabeda, J. C., Mendes, A. C., Calado, E., Castro, A. P., Ramos, M. H., Amorim, J. M., de Lencastre, H. (2007). Changes in the Clonal Nature and Antibiotic Resistance Profiles of Methicillin-Resistant Staphylococcus aureus Isolates Associated with Spread of the EMRSA-15 Clone in a Tertiary Care Portuguese Hospital. J. Clin. Microbiol. 45: 2881-2888 [Abstract] [Full Text]  
  • Cockfield, J. D., Pathak, S., Edgeworth, J. D., Lindsay, J. A. (2007). Rapid determination of hospital-acquired meticillin-resistant Staphylococcus aureus lineages. J Med Microbiol 56: 614-619 [Abstract] [Full Text]  
  • Moon, J.-S., Lee, A.-R., Kang, H.-M., Lee, E.-S., Kim, M.-N., Paik, Y. H., Park, Y. H., Joo, Y.-S., Koo, H. C. (2007). Phenotypic and Genetic Antibiogram of Methicillin-Resistant Staphylococci Isolated from Bovine Mastitis in Korea. J DAIRY SCI 90: 1176-1185 [Abstract] [Full Text]  
  • Gomes, A. R., Westh, H., de Lencastre, H. (2006). Origins and Evolution of Methicillin-Resistant Staphylococcus aureus Clonal Lineages.. Antimicrob. Agents Chemother. 50: 3237-3244 [Abstract] [Full Text]  
  • Huijsdens, X. W., van Santen-Verheuvel, M. G., Spalburg, E., Heck, M. E. O. C., Pluister, G. N., Eijkelkamp, B. A., de Neeling, A. J., Wannet, W. J. B. (2006). Multiple Cases of Familial Transmission of Community-Acquired Methicillin-Resistant Staphylococcus aureus.. J. Clin. Microbiol. 44: 2994-2996 [Abstract] [Full Text]  
  • Cho, D. T., Cha, H. Y., Chang, H.-H., Kim, S.-W., Chung, J. M., Kim, J., Lee, Y. C., Seol, S. Y., Lee, J. C. (2006). Risk factors for specific methicillin-resistant Staphylococcus aureus clones in a Korean hospital. J Antimicrob Chemother 57: 1122-1127 [Abstract] [Full Text]  
  • Chongtrakool, P., Ito, T., Ma, X. X., Kondo, Y., Trakulsomboon, S., Tiensasitorn, C., Jamklang, M., Chavalit, T., Song, J.-H., Hiramatsu, K. (2006). Staphylococcal Cassette Chromosome mec (SCCmec) Typing of Methicillin-Resistant Staphylococcus aureus Strains Isolated in 11 Asian Countries: a Proposal for a New Nomenclature for SCCmec Elements. Antimicrob. Agents Chemother. 50: 1001-1012 [Abstract] [Full Text]  
  • Koessler, T., Francois, P., Charbonnier, Y., Huyghe, A., Bento, M., Dharan, S., Renzi, G., Lew, D., Harbarth, S., Pittet, D., Schrenzel, J. (2006). Use of Oligoarrays for Characterization of Community-Onset Methicillin-Resistant Staphylococcus aureus.. J. Clin. Microbiol. 44: 1040-1048 [Abstract] [Full Text]  
  • Ip, M., Yung, R. W. H., Ng, T. K., Luk, W. K., Tse, C., Hung, P., Enright, M., Lyon, D. J. (2005). Contemporary Methicillin-Resistant Staphylococcus aureus Clones in Hong Kong. J. Clin. Microbiol. 43: 5069-5073 [Abstract] [Full Text]  
  • Soo Ko, K., Kim, Y.-S., Song, J.-H., Yeom, J.-S., Lee, H., Jung, S.-I., Jeong, D.-R., Kim, S.-W., Chang, H.-H., Ki, H. K., Moon, C., Oh, W. S., Peck, K. R., Lee, N. Y. (2005). Genotypic Diversity of Methicillin-Resistant Staphylococcus aureus Isolates in Korean Hospitals. Antimicrob. Agents Chemother. 49: 3583-3585 [Abstract] [Full Text]  
  • Cha, H. Y., Moon, D. C., Choi, C. H., Oh, J. Y., Jeong, Y. S., Lee, Y. C., Seol, S. Y., Cho, D. T., Chang, H.-H., Kim, S.-W., Lee, J. C. (2005). Prevalence of the ST239 Clone of Methicillin-Resistant Staphylococcus aureus and Differences in Antimicrobial Susceptibilities of ST239 and ST5 Clones Identified in a Korean Hospital. J. Clin. Microbiol. 43: 3610-3614 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»