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Journal of Clinical Microbiology, January 2005, p. 455-457, Vol. 43, No. 1
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.1.455-457.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

High Prevalence of Respiratory Viral Infections in Patients Hospitalized in an Intensive Care Unit for Acute Respiratory Infections as Detected by Nucleic Acid-Based Assays

Jérôme Legoff,1,2* Emmanuel Guérot,3 Angélique Ndjoyi-Mbiguino,1,4 Mathieu Matta,1 Ali Si-Mohamed,1,2 Laurent Gutmann,1 Jean-Yves Fagon,3 and Laurent Bélec1,2

Laboratoire de Virologie,1 Service de Réanimation Médicale, Hôpital Européen Georges Pompidou,3 Unité INSERM 430, Institut de Recherches Biomédicales des Cordeliers, Faculté de Médecine Broussais-Hôtel Dieu, Université Pierre et Marie Curie (Paris VI), Paris, France,2 Département de Microbiologie, Laboratoire National de Référence des Maladies Sexuellement Transmissibles et du SIDA, Faculté de Médecine, Université des Sciences de la Santé, Libreville, Gabon4

Received 8 April 2004/ Returned for modification 1 June 2004/ Accepted 24 September 2004

Forty-seven bronchoalveolar lavages (BAL) were obtained from 41 patients with acute pneumonia attending an intensive care unit. By molecular diagnosis, 30% of total BAL and 63% of bacteria-negative BAL were positive for respiratory viruses. Molecular detection allows for high-rate detection of respiratory viral infections in adult patients suffering from severe pneumonia.

* Corresponding author. Mailing address: Laboratoire de Microbiologie, Hôpital Européen Georges Pompidou, 20 Rue Leblanc, 75908 Paris Cedex 15, France. Phone: 331 56 09 39 58. Fax: 331 56 09 24 47. E-mail: jerome.le-goff{at}egp.ap-hop-paris.fr.

Journal of Clinical Microbiology, January 2005, p. 455-457, Vol. 43, No. 1
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.1.455-457.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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