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Journal of Clinical Microbiology, January 2005, p. 511-513, Vol. 43, No. 1
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.1.511-513.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Infant Botulism Acquired from Household Dust Presenting as Sudden Infant Death Syndrome

Department of Food and Environmental Hygiene,¹ Department of Forensic Medicine, University of Helsinki, Helsinki University,² National Public Health Institute, Helsinki, Finland,³ California Department of Health Services, Richmond, California⁴

Received 15 July 2004/ Returned for modification 25 July 2004/ Accepted 5 September 2004

Clostridium botulinum type B was detected by multiplex PCR in the intestinal contents of a suddenly deceased 11-week-old infant and in vacuum cleaner dust from the patient's household. C. botulinum was also isolated from the deceased infant's intestinal contents and from the household dust. The genetic similarity of the two isolates was demonstrated by pulsed-field gel electrophoresis and randomly amplified polymorphic DNA analysis, thereby confirming that dust may act as a vehicle for infant botulism that results in sudden death.

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