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Journal of Clinical Microbiology, October 2005, p. 5327-5331, Vol. 43, No. 10
0095-1137/05/$08.00+0 doi:10.1128/JCM.43.10.5327-5331.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.
Sequence-Based Typing of adeB as a Potential Tool To Identify Intraspecific Groups among Clinical Strains of Multidrug-Resistant Acinetobacter baumannii
Geert Huys,1*
Margo Cnockaert,1
Alexandr Nemec,2,3 and
Jean Swings1,4
Laboratory of Microbiology,1
BCCM/LMG Bacteria Collection, Ghent University, K. L. Ledeganckstraat 35, Ghent, Belgium,4
National Institute of Public Health,2
Department of Medical Microbiology, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic3
Received 20 May 2005/
Returned for modification 20 June 2005/
Accepted 22 July 2005
Sequence
analysis of an 850-bp fragment internal to the aspecific drug efflux
gene adeB revealed 11 sequence types (STs) among a collection
of 50 multidrug-resistant Acinetobacter baumannii (MDRAB)
strains, including members of pan-European clones I, II, and III. The
delineation of STs conformed with the intraspecific grouping of these
strains previously determined by different DNA fingerprinting methods.
Larger strain collections need to be screened to further explore the
potential of sequence-based adeB typing as a universal tool
for the monitoring of MDRAB
clones.
* Corresponding author. Mailing address: Laboratory of Microbiology, Ghent University,
K. L. Ledeganckstr. 35, B-9000 Gent, Belgium. Phone: 0032 9 2645131. Fax: 0032 9 2645092. E-mail:geert.huys{at}UGent.be.
Journal of Clinical Microbiology, October 2005, p. 5327-5331, Vol. 43, No. 10
0095-1137/05/$08.00+0 doi:10.1128/JCM.43.10.5327-5331.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.
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Copyright © 2005 by the American Society for Microbiology. All rights reserved.