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Journal of Clinical Microbiology, November 2005, p. 5804-5807, Vol. 43, No. 11
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.11.5804-5807.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Broth Microdilution Susceptibility Testing of Brucella Species: Quality Control Limits for Ten Antimicrobial Agents against Three Standard Quality Control Strains

Clinical Microbiology Institute, Wilsonville, Oregon

Received 7 March 2005/ Returned for modification 10 May 2005/ Accepted 14 June 2005

Brucella broth without supplementation is the recommended medium for broth microdilution susceptibility tests of Brucella abortus, B. melitensis, and B. suis. Based on an eight-laboratory collaborative study using a pH-adjusted modification of this medium, we propose MIC quality control ranges for three control strains against 10 antimicrobials that are potentially efficacious for treating infections caused by these agents of bioterrorism.

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