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Journal of Clinical Microbiology, December 2005, p. 6186-6188, Vol. 43, No. 12
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.12.6186-6188.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Toscana Virus Central Nervous System Infections in Southern Italy

Giuseppe Di Nicuolo,1* Pasquale Pagliano,2 Sonia Battisti,1 Maria Starace,1 Vera Mininni,1 Vittorio Attanasio,2 and Francesco Saverio Faella2

Virology Laboratory,1 Department of Neurological Infectious Diseases, D. Cotugno Hospital, Naples, Italy2

Received 30 May 2005/ Returned for modification 19 July 2005/ Accepted 16 September 2005

Toscana virus was detected by reverse transcription-nested PCR in 5.6% of cerebrospinal fluid (CSF) samples from patients with meningitis and encephalitis during the summer in southern Italy. The central nervous system infections were associated with young adults and with a substantially benign clinical course. Presenting features and CSF findings are also discussed in the present report.

* Corresponding author. Mailing address: Laboratory of Virology, D. Cotugno Hospital, Via G. Quagliariello 54, Naples 80131, Italy. Phone: 39 081 590 8403. Fax 39 081 590 8303. E-mail: giuseppe.dinicuolo{at}ospedalecotugno.it.

Journal of Clinical Microbiology, December 2005, p. 6186-6188, Vol. 43, No. 12
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.12.6186-6188.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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