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Journal of Clinical Microbiology, December 2005, p. 6197-6199, Vol. 43, No. 12
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.12.6197-6199.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Comparison of the Avidity Index Method and the Serologic Testing Algorithm for Recent Human Immunodeficiency Virus (HIV) Seroconversion, Two Methods Using a Single Serum Sample for Identification of Recent HIV Infections

Elisa Martró,1,2 Barbara Suligoi,3 Victoria González,2 Vincenzo Bossi,4 Anna Esteve,1 Joanne Mei,5 Vicenç Ausina,2* and the Recent HIV Infections Study Group

Center for Epidemiological Studies on HIV/AIDS of Catalonia (CEESCAT), Hospital Universitari Germans Trias i Pujol. Badalona, Spain,1 Microbiology Service, Hospital Universitari Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Badalona, Spain,2 Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy,3 Laboratory of Virology, Ospedale Amedeo di Savoia, Turin, Italy,4 Newborn Screening Quality Assurance Program, Centers for Disease Control and Prevention, Atlanta, Georgia5

Received 20 September 2005/ Returned for modification 22 September 2005/ Accepted 28 September 2005

A study was designed to compare an avidity index method to the serologic testing algorithm for recent human immunodeficiency virus (HIV) seroconversion (STARHS) for the detection of recent HIV infection. One hundred sixty HIV-positive sera were tested. Both techniques performed similarly in identifying recent infections, although STARHS tended to misclassify more individuals that had long-standing infection as being recently infected.


* Corresponding author. Mailing address: Microbiology Service. Hospital Universitari Germans Trias i Pujol. Ctra de Canyet, s/n 08916 Badalona, Spain. Phone: 34 933 478 894. Fax: 34 933 478 895. E-mail: vausina{at}ns.hugtip.scs.es.


Journal of Clinical Microbiology, December 2005, p. 6197-6199, Vol. 43, No. 12
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.12.6197-6199.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.




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