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Journal of Clinical Microbiology, February 2005, p. 978-981, Vol. 43, No. 2
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.2.978-981.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Diagnostic and Therapeutic Pitfalls Associated with Primaquine-Tolerant Plasmodium vivax

Jeanne M. Spudick,1 Lynne S. Garcia,2 David M. Graham,1 and David A. Haake1,3*

Veterans Affairs Greater Los Angeles Healthcare System,1 Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles,3 LSG & Associates, Santa Monica, California2

Received 19 June 2004/ Returned for modification 6 August 2004/ Accepted 30 September 2004

We describe a U.S. Army Ranger returning from duty in Afghanistan and Iraq with life-threatening infection due to Plasmodium vivax. Morphological variants were observed in blood films prepared using samples collected by venipuncture. The patient's multiple relapses indicate infection with primaquine-tolerant P. vivax. Strategies for relapse prevention using primaquine are reviewed.

* Corresponding author. Mailing address: Division of Infectious Diseases, 111F, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073. Phone: (310) 268-3814. Fax: (310) 268-4928. E-mail: dhaake{at}ucla.edu.

Journal of Clinical Microbiology, February 2005, p. 978-981, Vol. 43, No. 2
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.2.978-981.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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  • Baird, J. K. (2009). Resistance to Therapies for Infection by Plasmodium vivax. Clin. Microbiol. Rev. 22: 508-534 [Abstract] [Full Text]  
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  • HILL, D. R., BAIRD, J. K., PARISE, M. E., LEWIS, L. S., RYAN, E. T., MAGILL, A. J. (2006). PRIMAQUINE: REPORT FROM CDC EXPERT MEETING ON MALARIA CHEMOPROPHYLAXIS I.. Am J Trop Med Hyg 75: 402-415 [Abstract] [Full Text]  


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