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Journal of Clinical Microbiology, March 2005, p. 1426-1429, Vol. 43, No. 3
0095-1137/05/$08.00+0 doi:10.1128/JCM.43.3.1426-1429.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.
Department of Epidemiology and Preventive Medicine,1 Department of Pathology, School of Medicine, University of Maryland Baltimore,3 Veterans Affairs Maryland Health Care System, Baltimore, Maryland2
Received 12 July 2004/ Returned for modification 2 September 2004/ Accepted 27 October 2004
Vibrio cholerae can shift to a rugose colony phenotype, reflecting expression of an exopolysaccharide that provides protection against a variety of environmental stresses. Our data indicate that expression of the rugose phenotype is inhibited by a variety of sugars, including sucrose, dextrose, arabinose, fructose, and maltose. Inhibition by sucrose may be one factor in explaining the failure of rugose strains to grow on thiosulfate citrate bile salts sucrose agar, the primary selective medium for V. cholerae.
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